M4 Knick Resource: Automatic dissolved oxygen monitoring in bio-fermentation

Supplier Resource

Cellular fermentation requires precise conditions in a sterile environment. Many steps are taken to create an environment suitable for the proper molecular reactions to occur. Manually handling probes and other instrumentation risks compromising sterility. Frequent calibrations and manual cleanings can threaten sterility. Weeks of operation may be necessary to obtain the desired reaction and purification.

Introducing automated systems to the bio-fermentation process enables operators to maximize process efficiency and sterility.  Automated systems reduce the need for manual interventions, thereby reducing the risk of contamination. Consistently maintaining optimal pH and DO levels can lead to higher yields and faster production times.  And finally, precise control of pH and DO levels reduces the consumption of expensive reagents and raw materials, resulting in cost savings over time.

As a distributor for M4Knick, our team can work with you to determine the best products and solutions for your operation. Check out the full application note from M4Knick by viewing the PDF below and start a conversation with a Cross expert today to learn more!

M4 Knick Resource: Automatic dissolved oxygen monitoring in bio-fermentation 1

Are you interested in an M4Knick product? Fill out our contact form with some details about your application and we’ll have a specialist get in touch! Also, learn more about M4Knick as a products and solutions provider for Cross.

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In the meantime, enjoy these fun facts…

Did you know… Cross Company is an ESOP (Employee Stock Ownership Plan). Our ESOP started in 1979 and as of 2006, we are 100% employee-owned! Learn more about our ESOP and how that benefits both team members and our customers.
Did you know... the precision measurement group at Cross was founded in 1939 by our current CEO's grandfather, Jim King. That's a whole lot of calibration!
Did you know... A fingerprint weighs about 50 micrograms. We know, we weighed it! The residue left from a finger can actually make a difference in weight results which is why we wear gloves when we calibrate weights. For reference, a sheet of paper is about 4.5 grams, that’s 4.5 million micrograms.
Did you know… Cross Company has grown significantly since our start in 1954. Over the years we've acquired 26 companies! Today, our five groups have expertise in everything from industrial automation to precision measurement, and industry knowledge going all the way back to 1939.