M4Knick Application – Plasma Fractionation in the Pharmaceutical Industry

Supplier Resource

In the pharmaceutical industry, the process of blood plasma fractionation is both complex and critical. Precision isn’t just helpful—it’s essential. This is particularly true when it comes to pH control. Even minor inaccuracies can lead to massive product loss, compliance issues, or compromised sterility.

That’s where M4Knick’s automated pH measurement and control systems come into play.

This application note from M4Knick dives deep into how their suite of fully automated equipment — such as the SE 555 Memosens pH sensor, Sensogate WA 130H pneumatic holder, Unical 9000 controller, and Protos 4400 transmitter — all help pharmaceutical operations maintain accuracy, sterility, and efficiency in plasma fractionation.

One standout innovation is the cCare system, which enables automatic sensor retraction, cleaning, calibration, and reinsertion. This not only improves pH measurement accuracy but also reduces manual intervention, enhances data integrity, and supports full FDA compliance. The entire system is designed to thrive in CIP/SIP environments and support the rigorous demands of hygienic biotech applications.

As a distributor for M4Knick, our team can work with you to determine the best products and solutions for your operation. Check out the full application note from M4Knick and start a conversation with a Cross expert today to learn more!

See How A Solution From M4Knick Can Benefit Your Operation

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Did you know… Cross Company is an ESOP (Employee Stock Ownership Plan). Our ESOP started in 1979 and as of 2006, we are 100% employee-owned! Learn more about our ESOP and how that benefits both team members and our customers.
Did you know... the precision measurement group at Cross was founded in 1939 by our current CEO's grandfather, Jim King. That's a whole lot of calibration!
Did you know... A fingerprint weighs about 50 micrograms. We know, we weighed it! The residue left from a finger can actually make a difference in weight results which is why we wear gloves when we calibrate weights. For reference, a sheet of paper is about 4.5 grams, that’s 4.5 million micrograms.
Did you know… Cross Company has grown significantly since our start in 1954. Over the years we've acquired 26 companies! Today, our five groups have expertise in everything from industrial automation to precision measurement, and industry knowledge going all the way back to 1939.